Prognostic significance of macrophage infiltration in leiomyosarcomas

Cheng-Han Lee1, 2 †, Inigo Espinosa1†, SuzanVrijaldenhoven1,

Subbaya Subramanian1,Kelli D Montgomery1, Shirley Zhu1, Robert J Marinelli3, Johannes L Peterse 4, Neal Poulin2, Torsten O. Nielsen2, Rob B. West1,C. Blake Gilks2, Matt van de Rijn1.

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Supplemental data  

Web supplement Table 1: Clinicopathologic features of the fresh frozen LMS samples used for gene array analysis.

Web supplement Table 2:

Gene list for gene array analysis

Web supplement Table 3: Comparison of the CD68 and CD163 immunostaining results in all LMS.

Web supplement Figure 1: Whole tissue sections and corresponding 0.6 mm tissue cores showing LMS with A) case no.223: uniformly dense infiltrate of CD163 positive macrophages in the whole section and tissue core, B) case no.114: uniformly sparse infiltrate of CD163 positive macrophages in the whole section and tissue core. 

 

Web supplement Figure 2: Kaplan-Meier survival curves for the presence of tumor necrosis in (A) gynecologic and (B) non-gynecologic LMS.

Web supplement Figure 3: Kaplan-Meier survival curves by FNLCC grade in non-gynecologic LMS.