Table 2c: First 50 genes
with highest differential expression in PDGFRA mutant GISTs |
|
Gene |
Description |
Unigene ID |
Score(d) |
Fold Change |
SPON1 |
spondin 1, (f-spondin) extracellular matrix
protein |
Hs.5378 |
1.3506514 |
6.21778 |
IGFBP5 |
insulin-like growth factor binding protein
5 |
Hs.380833 |
1.3047165 |
5.54292 |
IGF1 |
insulin-like growth factor 1 (somatomedin
C) |
Hs.308053 |
1.2779636 |
3.76439 |
ANGPTL1 |
angiopoietin-like 1 |
Hs.304398 |
1.2254871 |
4.33414 |
LUM |
lumican |
Hs.406475 |
1.177386 |
4.36662 |
DLK1 |
delta-like 1 homolog (Drosophila) |
Hs.169228 |
1.1542304 |
1.47196 |
KIAA0534 |
KIAA0534 protein |
Hs.407474 |
1.1386462 |
4.35136 |
DKFZP434B044 |
hypothetical protein DKFZp434B044 |
Hs.262958 |
1.119748 |
3.99764 |
CLDN11 |
claudin 11 (oligodendrocyte transmembrane
protein) |
Hs.31595 |
1.0881825 |
4.64470 |
PDK4 |
pyruvate dehydrogenase kinase, isoenzyme 4 |
Hs.8364 |
1.0838902 |
3.44589 |
HNRPU |
heterogeneous nuclear
ribonucleoprotein U |
Hs.166463 |
1.0807383 |
1.56912 |
PPP2R1B |
protein phosphatase 2, regulatory subunit A
(PR 65), beta isoform |
Hs.431156 |
1.0601872 |
4.15235 |
SPOCK |
sparc/osteonectin,
cwcv and kazal-like domains proteoglycan |
Hs.93029 |
1.0459539 |
3.97131 |
PRSS2 |
protease, serine, 2 (trypsin 2) |
Hs.511525 |
1.0366911 |
5.40492 |
SORL1 |
sortilin-related receptor, L(DLR class) A
repeats-containing |
Hs.438159 |
1.0286613 |
4.03677 |
APOD |
apolipoprotein D |
Hs.75736 |
1.0268499 |
7.86234 |
TYROBP |
TYRO protein tyrosine kinase binding
protein |
Hs.9963 |
1.0154491 |
3.83288 |
FLJ20366 |
hypothetical protein FLJ20366 |
Hs.354793 |
0.9904725 |
3.71460 |
SULF1 |
sulfatase 1 |
Hs.409602 |
0.986583 |
3.07600 |
ECM1 |
extracellular matrix protein 1 |
Hs.81071 |
0.9745068 |
2.14016 |
MAPT |
microtubule-associated protein tau |
Hs.101174 |
0.9720159 |
6.59511 |
SCUBE2 |
signal peptide, CUB domain, EGF-like 2 |
Hs.435861 |
0.9648591 |
2.42009 |
VWF |
von Willebrand factor |
Hs.440848 |
0.9633689 |
3.89962 |
IGJ |
immunoglobulin J polypeptide, |
Hs.381568 |
0.9522969 |
3.26008 |
RARRES2 |
retinoic acid receptor responder
(tazarotene induced) 2 |
Hs.37682 |
0.9506683 |
3.05749 |
EGLN3 |
egl nine homolog 3 (C. elegans) |
Hs.443906 |
0.9455161 |
6.36850 |
C1QA |
complement component 1, q subcomponent,
alpha polypeptide |
Hs.9641 |
0.9451115 |
2.92682 |
IGLV |
immunoglobulin lambda variable group |
Hs.512116 |
0.9351256 |
3.52688 |
IL15RA |
interleukin 15 receptor, alpha |
Hs.12503 |
0.9346573 |
3.52773 |
MX1 |
myxovirus (influenza
virus) resistance 1 |
Hs.436836 |
0.8888529 |
4.02704 |
SEMA5A |
sema domain, seven
thrombospondin repeats (type 1 and type 1-like) |
Hs.27621 |
0.8863345 |
2.65311 |
LR8 |
LR8 protein |
Hs.190161 |
0.8843536 |
3.89467 |
EPB41L3 |
erythrocyte membrane protein band 4.1-like
3 |
Hs.103839 |
0.8784795 |
2.59129 |
CH25H |
cholesterol 25-hydroxylase |
Hs.47357 |
0.8775504 |
4.22944 |
TLE3 |
transducin-like enhancer of split 3 (E(sp1)
homolog, Drosophila) |
Hs.287362 |
0.8687078 |
2.92431 |
ISL1 |
ISL1 transcription factor, LIM/homeodomain,
(islet-1) |
Hs.505 |
0.8657636 |
2.47976 |
GPC5 |
glypican 5 |
Hs.450919 |
0.8629431 |
4.71517 |
AGT |
angiotensinogen |
Hs.19383 |
0.8609486 |
3.79877 |
FBLN1 |
fibulin 1 |
Hs.445240 |
0.860423 |
2.46420 |
JDP2 |
jun dimerization protein 2 |
Hs.154095 |
0.8602472 |
3.07592 |
CCL2 |
chemokine (C-C motif) ligand 2 |
Hs.303649 |
0.8582911 |
3.41990 |
SNK |
serum-inducible kinase |
Hs.398157 |
0.8553821 |
2.68625 |
WNT9A |
wingless-type MMTV integration site family,
member 9A |
Hs.149504 |
0.8548781 |
2.55467 |
APM2 |
adipose specific 2 |
Hs.511763 |
0.8518084 |
5.85456 |
PSMF1 |
proteasome (prosome, macropain) inhibitor
subunit 1 (PI31) |
Hs.437495 |
0.8514397 |
2.61767 |
KIAA0534 |
KIAA0534 protein |
Hs.407474 |
0.850514 |
4.75186 |
ISLR |
immunoglobulin superfamily containing
leucine-rich repeat |
Hs.102171 |
0.8503522 |
2.77383 |
NCF1 |
neutrophil cytosolic factor 1 |
Hs.458275 |
0.8468407 |
3.26218 |
STOM |
stomatin |
Hs.439776 |
0.8408588 |
3.05601 |
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