| Table 2a: First 50 genes with highest differential expression in
KIT exon 11 mutant GISTs |
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| Gene |
Description |
Unigene Id |
Score(d) |
Fold Change |
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| TM4SF12 |
transmembrane 4 superfamily member 12 |
Hs.16529 |
1.4343708 |
6.11278 |
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| DIO2 |
deiodinase, iodothyronine, type II |
Hs.436020 |
1.3718215 |
7.33664 |
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| CAPNS2 |
calpain small subunit 2 |
Hs.13359 |
1.3074648 |
5.38750 |
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| CCKBR |
cholecystokinin B receptor |
Hs.203 |
1.2563882 |
4.21661 |
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| LCN2 |
lipocalin 2 (oncogene 24p3) |
Hs.204238 |
1.2002276 |
5.07216 |
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| BLVRB |
**biliverdin reductase B (flavin reductase
(NADPH)) |
Hs.76289 |
1.1751826 |
5.45960 |
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| EHD4 |
EH-domain containing 4 |
Hs.55058 |
1.1646133 |
5.67989 |
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| MGC29898 |
hypothetical protein MGC29898 |
Hs.388749 |
1.1500615 |
5.20681 |
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| FLRT2 |
fibronectin leucine rich transmembrane
protein 2 |
Hs.48998 |
1.1337755 |
6.33282 |
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| GUCY1A3 |
guanylate cyclase 1, soluble, alpha 3 |
Hs.433488 |
1.1045856 |
3.29975 |
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| TM4SF9 |
transmembrane 4 superfamily member 9 |
Hs.8037 |
1.1039144 |
4.61288 |
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| PPP2R3A |
protein phosphatase 2 (formerly 2A),
regulatory subunit B'', alpha |
Hs.133234 |
1.1008696 |
8.09162 |
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| ROBO2 |
roundabout, axon guidance receptor, homolog
2 (Drosophila) |
Hs.31141 |
1.0970799 |
5.14947 |
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| GUCY1A3 |
guanylate cyclase 1, soluble, alpha 3 |
Hs.433488 |
1.0831366 |
4.01820 |
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| CD34 |
CD34 antigen |
Hs.374990 |
1.0823162 |
2.66837 |
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| B3GAT1 |
beta-1,3-glucuronyltransferase 1
(glucuronosyltransferase P) |
Hs.381050 |
1.0821947 |
4.39357 |
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| COL8A1 |
collagen, type VIII, alpha 1 |
Hs.114599 |
1.0747639 |
3.39593 |
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| WWP2 |
Nedd-4-like ubiquitin-protein ligase |
Hs.315485 |
1.0729466 |
5.10464 |
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| SNCAIP |
synuclein, alpha interacting protein
(synphilin) |
Hs.24948 |
1.0662587 |
3.91528 |
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| EVI1 |
ecotropic viral integration site 1 |
Hs.436019 |
1.0610498 |
6.23988 |
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| SLC21A6 |
solute carrier family 21 (organic anion
transporter), member 6 |
Hs.137425 |
1.0377796 |
3.61817 |
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| GRIN3A |
glutamate receptor, ionotropic,
N-methyl-D-aspartate 3A |
Hs.283852 |
1.0258401 |
10.30622 |
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| MAOA |
monoamine oxidase A |
Hs.183109 |
1.0221565 |
4.02053 |
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| MYCN |
v-myc myelocytomatosis viral related
oncogene, neuroblastoma derived (avian) |
Hs.25960 |
1.0119469 |
12.59488 |
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| SDCCAG33 |
serologically defined colon cancer antigen
33 |
Hs.284217 |
0.9968087 |
4.65098 |
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| PTGER3 |
prostaglandin E receptor 3 (subtype EP3) |
Hs.27860 |
0.9779319 |
4.26760 |
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| BMPR1A |
bone morphogenetic protein receptor, type
IA |
Hs.2534 |
0.9773508 |
3.99990 |
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| AUTS2 |
autism susceptibility candidate 2 |
Hs.296720 |
0.9760794 |
3.38653 |
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| PTPRD |
protein tyrosine phosphatase, receptor
type, D |
Hs.323079 |
0.9610238 |
3.11846 |
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| DSCR1L1 |
Down syndrome critical region gene 1-like 1
|
Hs.156007 |
0.9484743 |
2.61334 |
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| KIAA1233 |
KIAA1233 protein |
Hs.18705 |
0.9473329 |
2.98120 |
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| GJA12 |
gap junction protein, alpha 12, 47kDa |
Hs.100072 |
0.9350071 |
4.59277 |
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| LOC83690 |
CocoaCrisp |
Hs.436542 |
0.9044242 |
2.82651 |
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| C1QTNF7 |
C1q and tumor necrosis factor related
protein 7 |
Hs.153714 |
0.8964934 |
3.30323 |
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| DPP4 |
dipeptidylpeptidase 4 (CD26, adenosine
deaminase complexing protein 2) |
Hs.44926 |
0.8926644 |
5.57371 |
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| AR |
androgen receptor |
Hs.99915 |
0.8895907 |
2.78782 |
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| CAPN6 |
calpain 6 |
Hs.169172 |
0.8783318 |
4.98333 |
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| SYTL4 |
synaptotagmin-like 4 (granuphilin-a) |
Hs.376981 |
0.8686386 |
2.54623 |
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| RGS5 |
regulator of G-protein signalling 5 |
Hs.24950 |
0.8590866 |
3.17894 |
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| EBAF |
endometrial bleeding associated factor |
Hs.25195 |
0.8379553 |
1.89733 |
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| SDCCAG33 |
serologically defined colon cancer antigen
33 |
Hs.284217 |
0.8327929 |
3.67324 |
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| CIT |
citron (rho-interacting, serine/threonine
kinase 21) |
Hs.405932 |
0.8305713 |
3.29672 |
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| PLEKHE1 |
pleckstrin homology domain containing,
family E (with leucine rich repeats) member 1 |
Hs.38176 |
0.8257496 |
3.43921 |
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| SQRDL |
sulfide quinone reductase-like (yeast) |
Hs.435468 |
0.8180404 |
2.99402 |
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| EFS |
embryonal Fyn-associated substrate |
Hs.24587 |
0.8119308 |
2.26245 |
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| FLJ31978 |
hypothetical protein FLJ31978 |
Hs.12381 |
0.8101573 |
2.62416 |
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| SEMACAP3 |
likely ortholog of mouse semaF cytoplasmic
domain associated protein 3 |
Hs.177635 |
0.8079168 |
2.54872 |
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| SH3BGR |
SH3 domain binding glutamic acid-rich
protein |
Hs.47438 |
0.8032776 |
3.02500 |
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| DPT |
dermatopontin |
Hs.80552 |
0.8032766 |
1.85113 |
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