Tissue Microarray

TMA Home

Welcome to the web portal of the Stanford Tissue Microarray Consortium.

The tissue microarray images in this portal are part of the Stanford Tissue Microarray Database

Here in the portal you can access web supplements of tissue microarray-based papers that contain a browsable GeneExplorer-based scoring cluster and image database, along with any additional supporting material.

Please make a selection from the following:

25

Automated Analysis and Classification of Histological Tissue Features by Multi-dimensional Microscopic Molecular Profiling

Please see the web supplement for interactive access to images of all stained cores and associated visualizations.

Riordan DP, Varma S, West RB, Brown PO (2015) Automated Analysis and Classification of Histological Tissue Features by Multi-Dimensional Microscopic Molecular Profiling. PLoS ONE 10(7): e0128975. doi:10.1371/journal.pone.0128975


24

Systematic Analysis of Breast Cancer Morphology Uncovers Stromal Features Associated with Survival

Please see the web supplement for interactive access to images of all stained cores and associated figures.

AH Beck et al., Systematic Analysis of Breast Cancer Morphology Uncovers Stromal Features Associated with Survival, Sci. Transl. Med. 3, 108ra113 (2011).


23

Characterization of D-cyclin proteins in hematolymphoid neoplasms: lack of specificity of cyclin-D2 and D3 expression in lymphoma subtypes

Please see the web supplement for interactive access to images of all stained cores and associated figures.

Modern Pathology advance online publication 8 January 2010; doi: 10.1038/modpathol.2009.173


22

CD81 protein is expressed at high levels in normal germinal center B cells and in subtypes of human lymphomas

Please see the web supplement for interactive access to images of all stained cores.

Human Pathology, epub ahead of print (PMID: 20004001)


21

Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling

Please see the web supplement for interactive access to images of all stained cores and fgures.

Oncogene, doi: 10.1038/onc.2009.381


20

Coordinate Expression of Colony-Stimulating Factor-1 and Colony-Stimulating Factor-1-Related Proteins Is Associated with Poor Prognosis in Gynecological and Nongynecological Leiomyosarcoma

Please see the web supplement for interactive access to images of all stained cores and figures.

American Journal of Pathology, doi:10.2353/ajpath.2009.081037


19

The Macrophage Colony-Stimulating Factor 1 Response Signature in Breast Carcinoma

Please see the web supplement for interactive access to images of all stained cores, figures and supplementary data.

Clinical Cancer Research 15, 778-787, February 1, 2009. doi: 10.1158/1078-0432.CCR-08-1283


18

Diffuse Myogenin Expression by Immunohistochemistry is an Independent Marker of Poor Survival in Pediatric Rhabdomyosarcoma: A Tissue Microarray Study of 71 Primary Tumors Including Correlation With Molecular Phenotype

Please see the web supplement for interactive access to a cluster heatmap and images of all stained cores.

The American Journal of Surgical Pathology, August 14, 2008.


17

Immunohistochemical Characterization of Nasal-Type Extranodal NK/T-Cell Lymphoma Using a Tissue Microarray: An Analysis of 84 Cases

Please see the web supplement for figures, interactive access to images of all stained cores and supplemental data.

American Journal of Clinical Pathology Volume 130, Number 3 / September 2008..


16

Prognostic Significance of Macrophage Infiltration in Leiomyosarcomas

Please see the web supplement for figures, interactive access to images of all stained cores and supplemental data.

Clinical Cancer Research 14, 1423-1430, March 1, 2008.


15

A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors

Please see the web supplement for interactive access to images of all stained cores as well as figures, methods and tables.

American Journal of Surgical Pathology, February 2008, 32:2


14

Placental S100 (S100P) and GATA3: Markers for Transitional Epithelium and Urothelial Carcinoma Discovered by Complementary DNA Microarray

Please see the web supplement for interactive access to images of all stained cores as well as figures and tables.

American Journal of Surgical Pathology, May 2007, 31:5


13

Microvessel Density and Expression of Vascular Endothelial Growth Factor and Its Receptors in Diffuse Large B-Cell Lymphoma Subtypes

Please see the web supplement for interactive access to supplementary images.

Am J Pathol. 2007 Apr;170(4):1362-9.


12

Expression of the RNA-binding protein VICKZ in normal hematopoietic tissues and neoplasms

Please see the web supplement for interactive access to supplementary images.

haematologica 2007;91:176-183


11

The Oncoprotein LMO2 is Expressed in Normal Germinal Center B-Cells and i n Human B-Cell Lymphomas

Visit the web supplement for interactive access to supplementary images.

Blood First Edition Paper, prepublished online October 12, 2006


10

A tumor landscape effect in tenosynovial giant cell tumor from activation of CSF1 expressi on by a translocation in a minority of tumor cells

Visit the web supplement for interactive access to the raw data, full resolution downloadable images and supplemental material from the authors. Use GeneXplorer and CaseXplorer to interactively browse the Gene Microarray and Tissue Microarray data, including stained tissue cores.

PNAS published January 6, 2006, 10.1073/pnas.0507321103 (Medical Sciences), an Open Access article.


9

TMA-Combiner

This site describes the recently released TMA-Combiner, a software tool used in some of the projects described in this portal. This tool enables the TMA user to combine multiple replicates from one or more separate TMAs into a single dataset, with three score combination rules available to choose from. This tool is also described in detail at Modern Pathology, doi:10.1038/modpathol.3800491.


8

The Gene Expression Profile of Extraskeletal Myxoid Chondrosarcoma

Visit the web supplement for interactive access to the raw data and downloadable versions of all figures from the paper. In addition the authors provide supplementary data and images. The paper was published May, 2005 in Journal of Pathology 206. DOI: 10.1002/path.1792


7

Expression of the Human Germinal Center-Associated Lymphoma (HGAL) Protein, A New Marker of Germinal Center B Cell Derivation

Visit the web supplement for interactive access to supplementary images. This paper is a Blood First Edition Paper, prepublished online DOI 10.1182/blood-2004-08-3112.


6

Gastrointestinal Stromal Tumors (GISTs) with mutations in KIT and PDGFRA genes show distinct gene expression profiles.

Visit the web supplement for interactive access to raw data, figures and tables in the paper and supplementary figures and tables. The paper was published in 2004 in Oncogene 23(47), pp 7780-9.


5

Immunohistochemical and Clinical Characterization of the Basal-Like Subtype of Invasive Breast Carcinoma

The web supplement for this paper includes interactive access to the raw data and downloadable versions of all figures from the paper. The paper was published in 2004 in Clinical Cancer Research Vol. 10, pp 5367-5374.


4

Apo D in Soft Tissue Tumors: A Novel Marker for Dermatofibrosarcoma Protuberans.

The web supplement for this paper provides access to an interactive method to explore the clustered TMA data. The paper was published in 2004 in the American Journal of Surgical Pathology, Vol. 28, pp 1063-1069.


3

The novel marker, DOG1, is expressed ubiquitously in GI Stromal Tumors irrespective of KIT or PDGFA mutation status.

This site provides access to the figures from the paper and an interactive method to explore the clustered TMA data. The paper was published in 2004 in the American Journal of Pathology, Vol. 165, pp 107-113.


2

Synovial Sarcoma

Visit the web supplement to Nielsen et al., Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology. American Journal of Pathology, Vol. 163, No. 4, pp. 1449-1456.


1

Tissue Microarray Software Tools

This site describes the software tools used in the projects described in this portal. American Journal of Pathology, Vol. 161, No. 5, pp. 1557-1565.


Last edited on June 28, 2015 by RJM